I've had numerous occasion where one text option blocks the various buttons underneath. The latest, which led me to post this, involved an expedition as Marcus Garvey. I had an Animal Handler and two Chamosaurs and a Raptor. I had an enormous number of inventory slots. As I was exiting the map after finding the Golden Pyramid, I went to a Village to trade for a few items on the way out. The inventory slots blocked the buttons for "Deal" and "Cancel" in the trading screen, and I couldn't hit them.
I couldn't exit the trading screen. I tried pressing everything I could think of, but ultimately I just had to quit the game, losing my score and progression. It was going to be a very high-scoring game, and the first time I finished a game with Marcus Garvey on the highest difficulty. Very frustrating!